Fluoride Research Today is a free monthly online journal that collates and summarizes the latest research about Fluoride, including details on toothpaste, water, treatment, dangers.

Analysis of fluoride in toothpastes on the Belgian market.

Borremans M, Van Loco J, Van Den Meerssche P, Meunier J, Vrindts E, Goeyens L

Scientific Institute of Public Health, Brussels, Belgium. magda.borremans@iph.fgov.be

We developed a method for the quantitative determination of sodium fluoride (NaF), sodium monofluorophosphate (SMFP) and amine fluoride (AmF) in toothpastes on the Belgian market. Samples were suspended in water and the determination was made using anion chromatography with conductivity detection after chemical suppression. The described ion chromatographic method is an easy and reliable isocratic high-performance liquid chromatography method for the determination of total soluble fluoride content in toothpastes. The analytical repeatability and reproducibility, the matrix effects and the method's decision limit of three different toothpastes containing NaF, SMFP and AmF at a concentration close to the permitted one of 0.15 g % total F are determined. All the samples analysed are in conformity with the Cosmetics Directive 76/768/EC; none exceeds the limit of 0.15 g %.

Published 1 April 2008 in Int J Cosmet Sci, 30(2): 145-52.
Full-text of this article is available online (may require subscription).

Articles on Fluoride published 20 March 2008:

Modelling lifelong costs of caries with and without fluoride use.   Eur J Oral Sci, 116(2): 164-9.

Cost-benefit or cost-cost analyses are becoming increasingly important in dentistry. Therefore, the aim of the present study was to evaluate the economic consequences of caries prevention with fluorides. German epidemiological data were used in a system dynamics model to assess the lifelong costs of caries in a population. Without fluoride prevention, lifelong treatment for caries resulted in mean costs of 6,976 euro and a present value of 932 euro per person (5% discounting). In different ... [Abstract] [Full-text]

Articles on Fluoride published 11 March 2008:

Kinetics of fluoride release from and reuptake by orthodontic cements.   Am J Orthod Dentofacial Orthop, 133(3): 427-34.

INTRODUCTION: The purposes of this in-vitro study were to compare the fluoride-release profiles and the fluoride release, reuptake, and rerelease characteristics of orthodontic cements before and after topical fluoride treatment. METHODS: The orthodontic cements tested were 2 resin-modified glass ionomers (Vitremer [3M Dental Products, St Paul, Minn] and Fuji Ortho LC [GC Dental, Tokyo, Japan]), a glass ionomer (Ketac-Cem [Espe-Premier Dental Products, Norristown, Pa]), and a composite (Concise ... [Abstract] [Full-text]

SNOM images of X-ray radiographs at nano-scale stored in a thin layer of lithium fluoride.   J Microsc, 229: 490-5.

In this work, we report a method to observe soft X-ray radiographs at nanoscale of various kind of samples, biological and metallic, stored in a thin layer of lithium fluoride, employing scanning near-field optical microscopy with an optical resolution that reaches 50 nm. Lithium fluoride material works as a novel image detector for X-ray nano-radiographs, due to the fact that extreme ultraviolet radiation and soft X-rays efficiently produce stable point defects emitting optically stimulated ... [Abstract] [Full-text]

Articles on Fluoride published 31 January 2008:

Biomarkers of low-level exposure to soman vapor: comparison of fluoride regeneration to acetylcholinesterase inhibition.   Inhal Toxicol, 20(2): 149-56.

The nerve agent O-pinacolyl methylphosphonofluoridate, also known as soman or by its military designation GD, is a highly toxic organophosphorous compound that exerts its effects through inhibition of the enzyme acetylcholinesterase (AChE). In the present study, a fluoride ion based regeneration assay was developed to quantify the level of soman present in the blood of rats following a low-level whole-body inhalation exposure. It was hypothesized that the amount of regenerated nerve agent in ... [Abstract] [Full-text]

Articles on Fluoride published 30 January 2008:

Measured rates of fluoride/metal association correlate with rates of superoxide/metal reactions for Fe(III)EDTA(H2O)- and related complexes.   J Am Chem Soc, 130(5): 1727-34.

The effects of 10 paramagnetic metal complexes (Fe(III)EDTA(H2O)-, Fe(III)EDTA(OH)2-, Fe(III)PDTA-, Fe(III)DTPA2-, Fe(III)2O(TTHA)2-, Fe(III)(CN)6(3-), Mn(II)EDTA(H2O)2-, Mn(II)PDTA2-, Mn(II)beta-EDDADP2-, and Mn(II)PO4(-)) on F- ion 19F NMR transverse relaxation rates (R2 = 1/T2) were studied in aqueous solutions as a function of temperature. Consistent with efficient relaxation requiring formation of a metal/F- bond, only the substitution inert complexes Fe(III)(CN)6(3-) and Fe(III)EDTA(OH)2- ... [Abstract] [Full-text]

Articles on Fluoride published 21 January 2008:

Approximal fluoride concentration using different fluoridated products alone or in combination.   Caries Res, 42(1): 73-8.

The aim of the present investigation was to measure the approximal fluoride (F) concentration after using different F-containing products, either alone or in combination. Ten subjects participated on a total of 17 occasions, which were randomized, distributed and divided into two trials (called trial I and trial II). The F concentration was studied after treatment with toothpicks, dental flosses, an interdental brush dipped in 0.2 or 0.32% F gels, brushing with toothpaste containing 0.32% F and ... [Abstract] [Full-text]

The protective effect of TiF4, SnF2 and NaF against erosion-like lesions in situ.   Caries Res, 42(1): 68-72.

The aim of this in situ study was to compare the protective effect of TiF4, SnF2 and NaF on the development of erosion-like lesions in human enamel. Fourteen human molars were each divided into 4 specimens, mounted on acrylic mouth appliances and worn by 7 volunteers for 9 days. In order to mimic a feasible treatment procedure for patients with voluntary or involuntary gastric reflux, the specimens were etched for 2 min twice a day (0.01 M HCl) and fluoride applications were performed every ... [Abstract] [Full-text]

Influence of salivary macromolecules and fluoride on enamel lesion remineralization in vitro.   Caries Res, 42(1): 37-45.

The aim of this study was to investigate the influence of salivary macromolecules on enamel lesion remineralization in the presence or absence of fluoride. Paraffin-stimulated whole saliva was centrifuged, and the supernatant was dialyzed in 1,000 molecular-weight cutoff dialysis tubes, first against a phosphate buffer and then against a mineral solution containing Ca and phosphate. Artificial subsurface lesions of human enamel, created in pH 4.5 acetate buffer, were remineralized for 28 days ... [Abstract] [Full-text]

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